Pseudopterosin Biosynthesis: Aromatization of the Diterpene Cyclase Product, Elisabethatriene
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چکیده
منابع مشابه
Pseudopterosin Biosynthesis: Aromatization of the Diterpene Cyclase Product, Elisabethatriene
Putative precursors in pseudopterosin biosynthesis, the hydrocarbons isoelisabethatriene (10) and erogorgiaene (11), have been identified from an extract of Pseudopterogorgia elisabethae collected in the Florida Keys. Biosynthetic experiments designed to test the utilization of these compounds in pseudopterosin production revealed that erogorgiaene is transformed to pseudopterosins A-D. Togethe...
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Investigations are reported that identify the biosynthetic source and origins of the pseudopterosins, pharmacologically important diterpene glycosides, in the gorgonian coral Pseudopterogorgia elisabethae. We report here the isolation of physiologically significant levels of endogenous pseudopterosins A, B, C, and D from purified symbionts identified as the dinoflagellate Symbiodinium sp. Biosy...
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متن کاملIn vivo and in vitro investigations into the biosynthetic relatedness of the pseudopterosins.
[formula: see text] Both in vivo and in vitro techniques have been developed to test putative intermediates in the biosynthetic pathway to the pseudopterosins, antiinflammatory compounds isolated from Pseudopterogorgia elisabethae. Furthermore, specific activity data we have obtained indicate that pseudopterosin A is a precursor to pseudopterosins B, C, and D. We conclude that in the biosynthes...
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ژورنال
عنوان ژورنال: Marine Drugs
سال: 2003
ISSN: 1660-3397
DOI: 10.3390/md101054